Abstract:

Recent progresses in metagenomics have promoted a change of paradigm to investigate microbial ecosystems. These ecosystems are today analyzed by either their gene content or «who is there and who is not» from a taxonomical viewpoint. However, understanding the interactions between microbial communities and their environment well enough to be able to predict diversity on the basis of physicochemical parameters is a fundamental pursuit that requires dedicated computational approaches, as inspired from Systems Biology. This minar will illustrate 3 case studies of systems biology approaches, that once adapted, allows to better understand the role of microbes in a broader ecosystem context.